Replicative Fitness of SARS-CoV-2 Variants
Multiple lineages of SARS-CoV-2 have arisen since the initial spread of the virus in early 2020. Successive variants have replaced the original wild type of SARS-CoV-2. One hypothesis for the rapid spread of variants is that they have better replicative fitness, allowing faster growth to higher titres than wild-type virus in infected tissues. We have cultured samples from patients infected with each new variant of concern and local variants of interest in British Columbia. We performed growth curve experiments on viral isolates and wild-type virus. Our data suggest that SARS-CoV-2 variants do not show substantial differences in their growth in cell culture compared to the wild-type virus.
TEAM Samantha Kaweski, Martin Petric, Paul Levett
BCCDC POSTER PRESENTER
10/18/2021 3:25:00 PM
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