Respiratory outcomes 12 weeks after COVID-19 infection: a prospective cohort of hospitalised patients

TEAM: Drs. Aditi S Shah, Alyson W Wong, Cameron J Hague, Darra T Murphy, James C Johnston, Christopher J Ryerson and Christopher Carlsten Studies of Coronavirus disease 2019 (COVID-19) survivors in terms of residual lung pathophysiology are limited. Accordingly, we characterize chest CT and complete pulmonary function testing in a cohort of hospitalized COVID-19 patients 3 months after symptom onset. We show that majority of patients recovering after COVID-19 hospitalization have persistent lung function and chest imaging abnormalities 12 weeks after symptom onset. We also examined clinical predictors of persistent dyspnea and chest CT imaging abnormalities and demonstrate association between these clinical outcomes with days on oxygen supplementation that was used as a proxy of disease severity. Our findings demonstrate the need for early and aggressive intervention.

BC CDC Presenters

10/14/2020 6:15:00 PM