Dried Blood Spots to Measure SARS-CoV-2 and Endemic Human Coronavirus Seroreactivity

Dried blood spot collection offers a cheap and easily scaled means to measure SARS-CoV-2 seroreactvity from natural infection or immunization. We validated the performance of dried blood spot collection in a cross-sectional serological survey within British Columbia and report the diagnostic accuracy. Dried blood spot collected samples resulted by an electrochemiluminescence assay reliably detect SARS-CoV-2 antibodies against the viral Spike and Nucleocapsid proteins. Dried blood spot collected samples should be considered a valid alternative to serum from venipuncture to measure SARS-CoV-2 antibodies. TEAM Aidan Nikiforuk, Citlali Marquez, Brynn Millan Bonny So, Ella Chan, Agatha Jassem and the COVID-19 Immunity Task Force

BCCDC POSTER PRESENTER

10/18/2021 4:00:00 PM