Functional antibody responses following SARS-CoV-2 infections and vaccinations in pregnancy - Guadalein Tanunliong

SARS-CoV-2 infection during pregnancy leads to an increased risk of severe COVID-19 and adverse outcomes, while vaccination can offer maternal and infant protection. Most studies assess SARS-CoV-2 antibody levels alone, with limited research on antibody function in pregnancy. Using residual sera from pregnant individuals who were infected with and/or vaccinated against SARS-CoV-2, we assessed both antibody levels and antibody-dependent cellular phagocytosis activity against SARS-CoV-2 and the seasonal coronaviruses and explored their associations with clinical outcomes. Findings expand our understanding of pregnancy-specific immunity and may help guide future vaccine strategies.

BC CDC Presenter

11/4/2025 6:20:00 PM