A Real World Resistance Profile of Virologic Failures Collected from an International Collaboration (SHARED) 2019 Update
Anita Howe
Hepatitis C patients who failed Direct-Acting Antivirals (DAA) often selected
viruses with drug resistance-associated substitutions that limit treatment options.
SHARED, Surveillance of Hepatitis C Antiviral Resistance, Epidemiology
and Methodology, is an international collaboration to study HCV drug resistance
and transmission through sharing data, methods, software and technologies.
Recent data merger suggested that nearly 90% of the patients who failed
therapy selected resistant viruses, and novel mutations previously not observed
during clinical trials were detected in real-world clinic.
BC CDC Presenters
10/24/2019 6:05:00 PM
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