Guadalein Tanunliong - Longitudinal antibody responses to COVID-19 among women with varying SARS-CoV-2 infection and vaccination histories during pregnancy

COVID-19 in pregnancy can lead to worse disease severity and outcomes. The increased risk of preterm births and hospitalizations may be influenced by varying immune responses to SARS-CoV-2. We used residual sera from routine pregnancy screening to conduct a nested case-control study to explore SARS-CoV-2 antibodies. We found that at least 2 doses of vaccine induced higher antibody levels than infection alone. Hybrid immunity from infection and vaccination also showed higher antibody level trends, though not significant. Findings can be correlated with clinical data to inform associations with pregnancy outcomes, and may guide clinical care of pregnant women and vaccination booster campaigns.

Mediasite Presenter

10/27/2022 6:50:00 PM