Impact of direct-acting antiviral treatment on mortality related to extrahepatic manifestations

Chronic hepatitis C virus (HCV) infection is associated with an increased risk of deaths related to extrahepatic manifestations (EHM). The sustained virologic response (SVR) following the highly effective direct-acting antivirals (DAA) has been linked to decreased all-cause and liver-related mortality. However, evidence on the impact of DAA on EHM-related mortality is lacking. This analysis assessed the impact of DAA treatment and SVR on reducing mortality related to EHM using a large population-based, comprehensive linked administrative data in British Columbia, Canada. TEAM Dahn Jeong, Stanley Wong, Mohammad E. Karim, Sofia Bartlett, James Wilton, Jean D. Makuza, Héctor Alexander Velásquez García, Mawuena Binka, Hasina Samji, Amanda Yu, Maria Alvarez, Mel Krajden, Naveed Z. Janjua

BCCDC POSTER PRESENTER

10/18/2021 3:10:00 PM