Jessica Moe: Microdosing and Standard Dosing Take-Home Buprenophine from the Emergency Department: A Feasibility Study

Emergency department (ED) buprenorphine may prevent overdose. Microdosing is a novel method not requiring withdrawal, a barrier to standard inductions. We aimed to evaluate the feasibility of an ED buprenorphine program providing standard dosing and microdosing take-home packages, and of randomizing to these interventions. We screened ED patients for opioid use disorder and provided 21 standard dosing and 25 microdosing packages. At least 24% (standard dosing) and 32% (microdosing) remained on opioid agonist therapy at 30 days. We conclude that ED standard dosing and microdosing buprenorphine programs are feasible, and a randomized controlled trial would be acceptable to our population.

BC CDC Presenters

10/15/2020 5:20:00 PM